Real name: Akihiro
Akihiro was never given a chance at a normal life. He was born in blood and ripped out of his dead mother’s dead body by Romulus (more on him later). From that moment on, Daken was fed lies like Logan killed his mother and he never wanted him. Even after finding out it wasn’t true, Daken was too far gone. His hatred was so bad that he joined the Red Right Hand.
The fact it’s his son makes his actions harsher. It's good that they got a chance to reconcile and be a family during the Age of Krakoa.
4. Weapon X
Real name: Various members
This is where Wolverine was born. The monstrous scientists at Weapon X didn’t see Logan as human. He was an animal born to be experimented on. They bonded adamantium to his bones and continued to use him as a guinea pig.
Later, Weapon X reformed and made him a puppet again (Wolverine: The Return of Weapon X). They reactivated his implants and forced him to hunt and kill for them. What’s worst is, at some point, they’ll go after Logan again.
3. Lady Deathstrike
Real name: Yuriko Oyama
There are levels of hatred that some people shouldn’t pass. Not only did Yuriko Oyama pass them, but she burned the levels as she left.
Yuriko thought that Logan stole her father’s adamantium process (depending on the writer, this is partly true). With vengeance in her heart, she dedicated more than her life to killing Wolverine. She became more machine than human to fight her nemesis. It's a sad story, but there's also a lesson in letting things go.