Which superhero role can Jennifer Aniston still play?
Power Girl
Moving over to a DC superhero and sticking with the TV format, Aniston would be a great addition to the Arrowverse. Unbeknownst to the Arrowverse characters, there is a new multiverse. Whether Power Girl remains comic accurate and is from the new Earth-2 or not (the Star Girl series will be set here, with a Justice Society of America, so it could work) doesn’t necessarily matter. So long as an alternate Kara Zor-el (or Zor-L in this case) appears on Earth-Prime.
The heroes of Earth-Prime would now know the full scope of Oliver’s sacrifice from Crisis on Infinite Earths and we’d (hopefully) get a nice 2-3-episode arc on Supergirl with guest star Jennifer Aniston as Kara’s Earth-2 doppelganger. While our Kara has been around for a few years now, she still has a lot to learn. An older, more mature and level-headed version of herself could offer some words of wisdom to help fight off Leviathan or whatever danger is lurking in season 6.
Having Power Girl’s home be the new Earth-2 would also leave the door open for Aniston to appear on Stargirl, DC Universe’s upcoming drama—that will also see life on The CW—about high-schooler Courtney Whitmore who discovers a cosmic staff and follows in the heroic deeds of her stepfather. This new Earth-2 has ties to the Arrowverse already, having briefly appeared in Crisis on Infinite Earths, and Stargirl will be part of The CW’s lineup. It only makes sense that these characters will eventually interact with each other anyway.