12 greatest Spider-Man movie villains ranked from worst to best

Jake Gyllenhaal is Mysterio in Columbia Pictures' SPIDER-MAN: ™ FAR FROM HOME.
Jake Gyllenhaal is Mysterio in Columbia Pictures' SPIDER-MAN: ™ FAR FROM HOME. /
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Spider-Man: No Way Home, Shang-Chi and the Legend of the Ten Rings, Marvel, Marvel Cinematic Universe, MCU, Best Visual Effects Oscar
Doc Ock (Alfred Molina) and Spider-Man battle it out in Columbia Pictures’ SPIDER-MAN: NO WAY HOME. Courtesy of Sony Pictures. ©2021 CTMG. All Rights Reserved. MARVEL and all related character names: © & ™ 2021 MARVEL /

4. Otto Octavius

Movie: Spider-Man 2, Spider-Man: No Way Home

"“Sometimes, to do what’s right, we have to be steady and give up the thing we want the most. Even our dreams.”-Otto Octavius"

Otto Octavius is not a bad person. Before the experiment that turned him into a villain, he was a gentle man, a husband who loved his wife and had a passion for science. Then an experiment went wrong and turned him evil. From there, Doctor Octopus became one of Spider-Man’s greatest enemies.

Otto’s greatest attribute is his genius. Not just when it comes to creating machines. He knew how to plan. Spider-Man 2 showed that perfectly. First, he kidnapped MJ to throw Peter off his game. Then caused a runaway train to force Spider-Man to exhaust more energy than he’d like to. After that, there was nothing the Wall-Crawler could do. He may not have shown that devious genius in No Way Home, but he still displayed a high level of genius.

What put Otto so high on this list is more than what he did as a villain because he isn’t someone purely looking to hurt people. Alfred Molina being phenomenal is what put him in the top five. He may not have switched from evil to good frequently and with ease as the person at number one, but he did.

This writer will take it a step further. The Doctor Octopus character wouldn’t be what it is in the comics without him. Sure, people knew who he was. The arms are easily recognizable. What the creative team did in the movies was show that he was more than the arms. They gave him a personality that people would love to detest.